Recombinant ROCK2 Monoclonal Antibody
Product Specifications
Background
Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Abbreviation
ROCK2
UniProt
O75116
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human ROCK2 fragment
Target
KIAA; Rho kinase; Rho-associated protein kinase; ROCK2; ROCK-II; Rho kinase 2; Rho-associated; Rho-associated protein kinase 2; ROCK 2; Rock II; Rock2m; ROK alpha; ROKalpha; KIAA0619; B230113H15Rik; coiled coil containing protein kinase II; coiled-coil-containing protein kinase 2; mKIAA0619; p164 ROCK 2; p164 ROCK-2; Rho associated; Rho associated coiled coil containing protein kinase 2; Rho associated protein kinase 2; Rho-kinase
Clonality
Monoclonal,Recombinant
Clone
A352
Conjugation
Unconjugated
Applications
WB; IHC; IF; IP
Field of Research
Cell Biology; Signal Transduction; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100; IF 1:50; IP 1:25
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
160 kDa
Observed Molecular Weight
190-200 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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