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Recombinant ROCK2 Monoclonal Antibody

Product Specifications

Background

Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

Abbreviation

ROCK2

UniProt

O75116

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human ROCK2 fragment

Target

KIAA; Rho kinase; Rho-associated protein kinase; ROCK2; ROCK-II; Rho kinase 2; Rho-associated; Rho-associated protein kinase 2; ROCK 2; Rock II; Rock2m; ROK alpha; ROKalpha; KIAA0619; B230113H15Rik; coiled coil containing protein kinase II; coiled-coil-containing protein kinase 2; mKIAA0619; p164 ROCK 2; p164 ROCK-2; Rho associated; Rho associated coiled coil containing protein kinase 2; Rho associated protein kinase 2; Rho-kinase

Clonality

Monoclonal,Recombinant

Clone

A352

Conjugation

Unconjugated

Applications

WB; IHC; IF; IP

Field of Research

Cell Biology; Signal Transduction; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:100; IF 1:50; IP 1:25

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

160 kDa

Observed Molecular Weight

190-200 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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