Recombinant PU.1 Monoclonal Antibody
Product Specifications
Background
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
Abbreviation
PU.1
UniProt
P17947
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human PU.1 fragment
Target
Spi; SPI1;31 kDa Transforming Protein;31 kDa-transforming protein; cb1086; Hematopoietic transcription factor PU.1; homolog of; mouse; oncogene spi1; PU.1; SFFV virus-induced murine erythroleukemia oncogene; SFPI1; si:by184l24.2; SPI 1; SPI 1 proto oncogene; SPI A; Spleen focus forming virus (SFFV) proviral integration oncogene spi1; Spleen focus forming virus proviral integration oncogene spi1; Transcription factor PU.1; transcription factor spi1
Clonality
Monoclonal,Recombinant
Clone
A347
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
31 kDa
Observed Molecular Weight
42 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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