Recombinant PTBP2 Monoclonal Antibody
Product Specifications
Background
RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Abbreviation
PTBP2
UniProt
Q9UKA9
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human PTBP2 fragment
Target
PTBP; PTBP2; PTBLP; brPTB; nPTB; PTB
Clonality
Monoclonal,Recombinant
Clone
A342
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Neuroscience
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57 kDa
Observed Molecular Weight
57 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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