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Recombinant PHF20 Monoclonal Antibody

Product Specifications

Background

Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity) . As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.

Abbreviation

PHF20

UniProt

Q9BVI0

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant human PHB2 fragment

Target

HCA; PHF; GLEA; C20orf; PHF20; C20orf104; GLEA2; HCA58; NZF; TDRD20A; TZP

Clonality

Monoclonal,Recombinant

Clone

A331

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/0jofSGwa

Calculated Molecular Weight

150 kDa

Observed Molecular Weight

150 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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