Recombinant PHF20 Monoclonal Antibody
Product Specifications
Background
Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity) . As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
Abbreviation
PHF20
UniProt
Q9BVI0
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human PHB2 fragment
Target
HCA; PHF; GLEA; C20orf; PHF20; C20orf104; GLEA2; HCA58; NZF; TDRD20A; TZP
Clonality
Monoclonal,Recombinant
Clone
A331
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
150 kDa
Observed Molecular Weight
150 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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