Recombinant PELP1 Monoclonal Antibody
Product Specifications
Background
Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1.
Abbreviation
PELP1
UniProt
Q8IZL8
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human PELP1 fragment
Target
HMX; PELP; PELP1; MNAR; P160; proline; HMX3
Clonality
Monoclonal,Recombinant
Clone
A328
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
120 kDa
Observed Molecular Weight
160 kDa
Isotype
IgG, κ
Available Sizes
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