Recombinant PELP1 Monoclonal Antibody

Product Specifications

Background

Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1.

Abbreviation

PELP1

UniProt

Q8IZL8

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human PELP1 fragment

Target

HMX; PELP; PELP1; MNAR; P160; proline; HMX3

Clonality

Monoclonal,Recombinant

Clone

A328

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

120 kDa

Observed Molecular Weight

160 kDa

Isotype

IgG, κ

Available Sizes

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