Recombinant Myosin Light Chain 3 Monoclonal Antibody
Product Specifications
Background
MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury.
Abbreviation
Myosin Light Chain 3
UniProt
P08590
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human Myosin Light Chain 3 fragment
Target
Myl; MYL3; alkali; Cardiac myosin light chain 1; CMH8; CMLC1; ELC of myosin; Essential light chain of myosin; light chain 1; light chain 3; light polypeptide 3; MLC1SB; MLC1V; Myosin; Myosin light chain 1; Myosin light chain 1 slow; Myosin light chain 1 slow twitch muscle B/ventricular isoform; Myosin light chain 3; OTTHUMP00000165922; skeletal; slow; Slow skeletal ventricular myosin alkali light chain 3; slow-twitch muscle B/ventricular isoform; ventricular; Ventricular/slow twitch myosin alkali light chain; VLC1
Clonality
Monoclonal,Recombinant
Clone
A310
Conjugation
Unconjugated
Applications
WB; IHC; FCM
Field of Research
Signal Transduction; Cardiovascular
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
22 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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