Recombinant MSH2 Monoclonal Antibody
Product Specifications
Background
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
MSH2
UniProt
P43246
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human MSH2 fragment
Target
FCC; MSH; COCA; LCFS; mutS homolog; MSH2; COCA1; FCC1; HNPCC; HNPCC1; LCFS2; mutS homolog 2; COCA1; FCC1; HNPCC; HNPCC1; LCFS2; mutS homolog 2; MSH2; COCA1; FCC1; HNPCC; HNPCC1; LCFS2
Clonality
Monoclonal,Recombinant
Clone
A307
Conjugation
Unconjugated
Applications
WB; IHC; IF; IP
Field of Research
Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50; IF 1:50-1:100; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
105 kDa
Observed Molecular Weight
104 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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