Recombinant MCM5 Monoclonal Antibody

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP.

MGC; Cell division cycle; DNA replication licensing factor MCM; Minichromosome maintenance complex component; P1-CDC; P1 CDC; CDC; MCM; MCM5; CDC46; P1-CDC46; CDC 46; CDC46 homolog; Cell division cycle 46; DNA replication licensing factor; DNA replication licensing factor MCM5; MCM 5; MGC5315; Minichromosome maintenance complex component 5; P1 CDC46; DNA replication licensing factor MCM 5; Minichromosome maintenance complex component 5; Minichromosome maintenance deficient (S. cerevisiae) 5; Minichromosome maintenance deficient 5; Minichromosome maintenance deficient protein 5