Recombinant MCM3 Monoclonal Antibody

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

HCC; DNA replication licensing factor MCM; DNA polymerase alpha holoenzyme-associated protein P; P1-MCM; MCM; MCM3; HCC5; P1-MCM3; P1.h; RLFB; MCM 3; P1 Protein; P102 protein; p102; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1; RLF subunit beta; Cervical cancer proto oncogene 5; DNA polymerase alpha holoenzyme associated P1; DNA polymerase alpha holoenzyme associated protein P1; DNA replication factor MCM3; HCC 5; hRlf beta subunit; Human cervical cancer proto oncogene 5; MCM3 minichromosome maintenance deficient 3; MGC1157; Minichromosome maintenance complex component 3; Minichromosome maintenance deficient 3; Minichromosome maintenance protein 3; P1 h; P1 MCM3; Replication licensing factor beta subunit; RLF beta subunit