Recombinant KRAS Monoclonal Antibody
Product Specifications
Background
KRAS, a Ras protein, binds GDP/GTP and possesses intrinsic GTPase activity; It plays an important role in the regulation of cell proliferation and in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
Abbreviation
KRAS
UniProt
P01116
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human KRAS fragment
Target
CFC; K-Ras; KRAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD; RASK2; c-Ki-ras2; GTPase KRas; RASK; c-Ki-ras; K-Ras 2; c Ki ras2; c Kirsten ras protein; Cellular c Ki ras2 proto oncogene; Cellular transforming proto oncogene; cK Ras; GTPase; K RAS p21 protein; K RAS2A; K RAS2B; K RAS4A; K RAS4B; KI RAS; KIRSTEN MURINE SARCOMA VIRUS 2; Kirsten rat sarcoma 2 viral (v Ki ras2) oncogene homolog; Kirsten rat sarcoma viral oncogene homolog; KRAS proto oncogene; N-terminally processed; Oncogene KRAS2; p21ras; PR310 c K ras oncogene; PR310 cK ras oncogene; Transforming protein p21; v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v Ki ras2 Kirsten rat sarcoma viral oncogene homolog
Clonality
Monoclonal,Recombinant
Clone
A282
Conjugation
Unconjugated
Applications
WB; IF; IP
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IF 1:50; IP 1:25-1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
21 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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