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Recombinant KRAS Monoclonal Antibody

Product Specifications

Background

KRAS, a Ras protein, binds GDP/GTP and possesses intrinsic GTPase activity; It plays an important role in the regulation of cell proliferation and in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.

Abbreviation

KRAS

UniProt

P01116

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human KRAS fragment

Target

CFC; K-Ras; KRAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD; RASK2; c-Ki-ras2; GTPase KRas; RASK; c-Ki-ras; K-Ras 2; c Ki ras2; c Kirsten ras protein; Cellular c Ki ras2 proto oncogene; Cellular transforming proto oncogene; cK Ras; GTPase; K RAS p21 protein; K RAS2A; K RAS2B; K RAS4A; K RAS4B; KI RAS; KIRSTEN MURINE SARCOMA VIRUS 2; Kirsten rat sarcoma 2 viral (v Ki ras2) oncogene homolog; Kirsten rat sarcoma viral oncogene homolog; KRAS proto oncogene; N-terminally processed; Oncogene KRAS2; p21ras; PR310 c K ras oncogene; PR310 cK ras oncogene; Transforming protein p21; v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v Ki ras2 Kirsten rat sarcoma viral oncogene homolog

Clonality

Monoclonal,Recombinant

Clone

A282

Conjugation

Unconjugated

Applications

WB; IF; IP

Field of Research

Signal Transduction; Epigenetics and Nuclear Signaling; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IF 1:50; IP 1:25-1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22 kDa

Observed Molecular Weight

21 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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