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Recombinant ING5 Monoclonal Antibody

Product Specifications

Background

Inhibitor of growth protein 5 is a protein that in humans is encoded by the ING5 gene. The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.

Abbreviation

ING5

UniProt

Q8WYH8

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human ING5 fragment

Target

ING; p28ING; ING5; p28ING5

Clonality

Monoclonal,Recombinant

Clone

A265

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

32 kDa

Observed Molecular Weight

32 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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