Recombinant IMPDH2 Monoclonal Antibody
Product Specifications
Background
Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene.IMP dehydrogenase 2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 has been identified as an intracellular target of the natural product sanglifehrin A.
Abbreviation
IMPDH2
UniProt
P12268
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human IMPDH2 fragment
Target
IMPD; IMPDH; IMPDH2; IMPD2; IMPDH-II; IMDH2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP oxireductase 2; IMPD 2; IMPDH 2; IMPDH II; Inosine 5' monophosphate dehydrogenase 2; Inosine 5' phosphate dehydrogenase 2; Inosine monophosphate dehydrogenase type II; Inosine-5''-monophosphate dehydrogenase 2
Clonality
Monoclonal,Recombinant
Clone
A264
Conjugation
Unconjugated
Applications
WB; IF; IP
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IF 1:50; IP 1:25-1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56 kDa
Observed Molecular Weight
56 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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