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Recombinant Histone H1 (CT) Monoclonal Antibody

Product Specifications

Background

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

Abbreviation

Histone H1

UniProt

P10412

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to the C-terminus of human histone H1.4 protein

Target

H1F; H1s; H1-; dJ221C; H1.4; H1E; H1F4; H1s-4; dJ221C16.5; RMNS; HIST1H1E; H1-4; dJ221C16.5; H1.4; H1F4; H1s-4; HIST1H1E; RMNS

Clonality

Monoclonal,Recombinant

Clone

A247

Conjugation

Unconjugated

Applications

WB; IHC; IF; FCM

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:200; IF 1:50; FCM 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

30 kDa

Observed Molecular Weight

30 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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