Recombinant GRP94 Monoclonal Antibody

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD) . Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.

HEL; TRA; GRP; HSP90B; HSP90B1; ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1; endoplasmin; ECGP; endoplasmin; GP96; GRP94; HEL35; HEL-S-125m; TRA1;90 kDa;94 kDa glucose regulated protein;94 kDa glucose-regulated protein; beta; Endothelial cell (HBMEC) glycoprotein; ENPL; ERp99; Glucose regulated protein 94kDa; gp96 homolog; GRP 94; GRP-94; Heat shock protein; Heat shock protein 90 kDa beta member 1; heat shock protein 90kDa beta (Grp94) ; Heat shock protein 90kDa beta member 1; member 1; Stress inducible tumor rejection antigen GP96; tumor rejection antigen (gp96) 1; Tumor rejection antigen 1; Tumor rejection antigen gp96; Tumor rejection antigen-1 (gp96)