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Recombinant GOT2 Monoclonal Antibody

Product Specifications

Background

Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT2 is a major participant in the malate-aspartate shuttle, which is a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation, especially in terms of tumor growth.

Abbreviation

GOT2

UniProt

P00505

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human GOT2 fragment

Target

KAT; GOT; KYAT; GOT2; KAT4; KATIV; KYAT4; mitAAT; AATM; AL022787; Aspartate aminotransferase; Aspartate aminotransferase 2; Aspartate transaminase 2; ASPATA; EC 2.6.1.1; FABP 1; FABP pm; FABP-1; FABPpm; Fatty acid binding protein; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase; Glutamate oxaloacetate transaminase 2; Glutamic oxaloacetic transaminase 2; Got 2; kynurenine aminotransferase 4; Kynurenine aminotransferase IV; kynurenine--oxoglutarate transaminase 4; kynurenine--oxoglutarate transaminase IV; mAspAT; MGC102129; MGC115763; mitochondrial; mitochondrial (aspartate aminotransferase 2) ; Mitochondrial aspartate aminotransferase; OTTMUSP00000017748; Plasma membrane fatty acid binding protein; Plasma membrane-associated fatty acid-binding protein; Transaminase A

Clonality

Monoclonal,Recombinant

Clone

A237

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Signal Transduction; Cancer; Metabolism

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa

Observed Molecular Weight

42 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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