Recombinant GOT2 Monoclonal Antibody
Product Specifications
Background
Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT2 is a major participant in the malate-aspartate shuttle, which is a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation, especially in terms of tumor growth.
Abbreviation
GOT2
UniProt
P00505
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human GOT2 fragment
Target
KAT; GOT; KYAT; GOT2; KAT4; KATIV; KYAT4; mitAAT; AATM; AL022787; Aspartate aminotransferase; Aspartate aminotransferase 2; Aspartate transaminase 2; ASPATA; EC 2.6.1.1; FABP 1; FABP pm; FABP-1; FABPpm; Fatty acid binding protein; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase; Glutamate oxaloacetate transaminase 2; Glutamic oxaloacetic transaminase 2; Got 2; kynurenine aminotransferase 4; Kynurenine aminotransferase IV; kynurenine--oxoglutarate transaminase 4; kynurenine--oxoglutarate transaminase IV; mAspAT; MGC102129; MGC115763; mitochondrial; mitochondrial (aspartate aminotransferase 2) ; Mitochondrial aspartate aminotransferase; OTTMUSP00000017748; Plasma membrane fatty acid binding protein; Plasma membrane-associated fatty acid-binding protein; Transaminase A
Clonality
Monoclonal,Recombinant
Clone
A237
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
42 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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