Recombinant GOT1 Monoclonal Antibody

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST) . Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

GIG; GOT; ASTQTL; GOT1; AST1; ASTQTL1; GIG18; cAspAT; cCAT; AAT; ASAT; AspAT; serum glutamic oxaloacetic transaminase; SGOT; AST; cytoplasmic; Glut; Aspartate aminotransferase; AATC; Aspartate aminotransferase 1; Aspartate aminotransferase cytoplasmic; Aspartate aminotransferase cytosolic; cysteine aminotransferase; cysteine transaminase; cytoplasmic (cCAT) ; ec 2.6.1.1; GIG 18; Glutamate oxaloacetate transaminase 1; Glutamate oxaloacetate transaminase soluble; Glutamic oxaloacetic transaminase 1 soluble; GOT 1; Growth inhibiting protein 18; Transaminase A