Recombinant GOSR1/GS28 Monoclonal Antibody
Product Specifications
Background
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14) . Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Abbreviation
GOSR1/GS28
UniProt
O95249
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human GOSR1/GS28 fragment
Target
GOSR; GOLIM; GOS28/P; GOS; GOSR1; GOLIM2; GOS-28; GOS28; GOS28/P28; GS28; P28
Clonality
Monoclonal,Recombinant
Clone
A235
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM
Field of Research
Neuroscience; Signal Transduction
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:100; IF 1:50; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
29 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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