Recombinant FOXA1 Monoclonal Antibody
Product Specifications
Background
Forkhead transcription factor (FOXA1) is a pioneering factor in the development of some organs and certain cancers. It opens tight chromatin by interacting with nucleosomal core histones. FOXA1 can bind to cis-acting elements and recruit other transcription factors to induce transcription. FOXA1 is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues, and participates in the development of a variety of endoderm-derived organ systems, such as liver, pancreas, lung and prostate. FOXA1 is related to many diseases and plays a role in hormone-dependent diseases such as breast cancer and prostate cancer.
Abbreviation
FOXA1
UniProt
P55317
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human FOXA1 fragment
Target
FOXA; FOXA1; HNF3A; TCF3A
Clonality
Monoclonal,Recombinant
Clone
A223
Conjugation
Unconjugated
Applications
WB; IHC; FCM
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
49 kDa
Observed Molecular Weight
52 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
