Recombinant eRF3/GSPT1 Monoclonal Antibody
Product Specifications
Background
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
Abbreviation
ERF3/GSPT1
UniProt
P15170
Host
Rabbit
Reactivity
Human; Rat; Mouse; Monkey
Immunogen
Recombinant human eRF3/GSPT1 fragment
Target
GSPT; ERF3A; GSPT1
Clonality
Monoclonal,Recombinant
Clone
A210
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56 kDa
Observed Molecular Weight
80 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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