Recombinant CLPP Monoclonal Antibody
Product Specifications
Background
Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.
Abbreviation
CLPP
UniProt
Q16740
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human CLPP fragment
Target
DFNB; PRLTS; CLPP; DFNB81; PRLTS3; ATP-dependent Clp protease proteolytic subunit; mitochondrial
Clonality
Monoclonal,Recombinant
Clone
A191
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
26 kDa
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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