Recombinant Cleaved PARP1 p85 Monoclonal Antibody
Product Specifications
Background
Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage.
Abbreviation
Cleaved PARP1 p85
UniProt
P09874
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human Cleaved PARP1 p85 fragment
Target
SCA; ARTD; Poly[ADP-ribose] synthase; Poly ADP ribose polymerase; poly (ADP-ribose) polymerase; Poly [ADP-ribose] polymerase; NAD (+) ADP-ribosyltransferase; ADP-ribosyltransferase diphtheria toxin-like; pADPRT; ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1; PARP1; Cleaved PARP; ADP-ribosyltransferase diphtheria toxin-like 1; APOPAIN; NAD (+) ADP-ribosyltransferase 1; Poly [ADP-ribose] polymerase 1; Poly ADP ribose polymerase 1; poly (ADP-ribose) polymerase 1; Poly[ADP-ribose] synthase 1; SCA1; ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase 1; PPOL
Clonality
Monoclonal,Recombinant
Clone
A190
Conjugation
Unconjugated
Applications
WB; IF; FCM; IP
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IF 1:100-1:200; FCM 1:50-1:100; IP 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/UfTb6IrE
Calculated Molecular Weight
85kDa
Observed Molecular Weight
89kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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