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Recombinant Cleaved PARP1 p85 Monoclonal Antibody

Product Specifications

Background

Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage.

Abbreviation

Cleaved PARP1 p85

UniProt

P09874

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human Cleaved PARP1 p85 fragment

Target

SCA; ARTD; Poly[ADP-ribose] synthase; Poly ADP ribose polymerase; poly (ADP-ribose) polymerase; Poly [ADP-ribose] polymerase; NAD (+) ADP-ribosyltransferase; ADP-ribosyltransferase diphtheria toxin-like; pADPRT; ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1; PARP1; Cleaved PARP; ADP-ribosyltransferase diphtheria toxin-like 1; APOPAIN; NAD (+) ADP-ribosyltransferase 1; Poly [ADP-ribose] polymerase 1; Poly ADP ribose polymerase 1; poly (ADP-ribose) polymerase 1; Poly[ADP-ribose] synthase 1; SCA1; ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase 1; PPOL

Clonality

Monoclonal,Recombinant

Clone

A190

Conjugation

Unconjugated

Applications

WB; IF; FCM; IP

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IF 1:100-1:200; FCM 1:50-1:100; IP 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

85kDa

Observed Molecular Weight

89kDa

Isotype

IgG, κ

Available Sizes

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