Recombinant CD79b Monoclonal Antibody
Product Specifications
Background
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Abbreviation
CD79b
UniProt
P40259
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD79b fragment
Target
AGM; B-Cell-Specific Glycoprotein B; CD79B; AGM6; B29; IGB; B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; B29; Ig&beta
Clonality
Monoclonal,Recombinant
Clone
A182
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM
Field of Research
Immunology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50; FCM 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
14, 30-50 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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