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Recombinant CD59 Monoclonal Antibody

Product Specifications

Background

CD59 is a widely expressed membrane regulatory protein, and its C-terminus is fixed on the cell surface via a GPI anchor. CD59 has different names due to its functions, such as homologous restriction factor-20, protectin and membrane inhibitor of reactive lysis (MIRL) . The main physiological function of CD59 is to prevent the complement membrane attack complex (MAC) from lysing and destroying cells of the same species or its own, that is, homologous species restriction (HSR) .

Abbreviation

CD59

UniProt

P13987

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human CD59 fragment

Target

MEM; MIC; MSK; p18;16.3A; MIC11MSK; HRF; MIN; CD59;16.3A5;1F5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20;1F5 antigen;20 kDa homologous restriction factor; CD59 antigen; CD59 glycoprotein; FLJ38134; FLJ92039; HRF 20; Ly 6; MIC11MSK21; Protectin; H19;1F-5Ag; CD 59; CD_antigen=CD59; CD59 antigen complement regulatory protein; CD59 antigen p18 20; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5; CD59 molecule; CD59 molecule complement regulatory protein; Cd59a; Complement regulatory protein; EL32 and G344) ; Human leukocyte antigen MIC11; Ly 6; Ly 6 like protein; Lymphocytic antigen CD59/MEM43; MAC inhibitory protein; MAC IP; MAC-inhibitory protein; MACIP; MEM43 antigen; Membrane attack complex (MAC) inhibition factor; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MGC2354; p18 20; Surface antigen recognized by monoclonal 16.3A5; T cell activating protein

Clonality

Monoclonal,Recombinant

Clone

A178

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology; Signal Transduction; Stem Cells; Cardiovascular

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:200-1:1000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

14 kDa

Observed Molecular Weight

18 kDa

Isotype

IgG, κ

Available Sizes

Frequently Asked Questions

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