Recombinant CD41 Monoclonal Antibody

Integrin α-IIb/β-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness.

HPA; PPP1R; ITGA2B; BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93; GPalpha Iib; Integrin alpha-Iib; Platelet membrane glycoprotein Iib; ITGAB; &alpha-IIb integrin-n; BDPLT16; alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex; alpha subunit; antigen CD41; antigen CD41) ; form 2; Integrin; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; integrin αIIbβ3; ITA2B; platelet fibrinogen receptor; platelet glycoprotein IIb of IIb/IIIa complex; platelet specific antigen BAK