Recombinant CD35 Monoclonal Antibody

Product Specifications

Background

CD35, also known as complement receptor 1 (CR1), is a 220-300 kDa N-glycosylated member of the RCA (regulators of complement activation) family of proteins. CD35 binds and internalizes particles and immune complexes that are opsonized with MBL or complement components C3b, C3i, C4b, or C1q. CD35 additionally protects the cell from complement-mediated lysis by serving as a cofactor for Factor I and inhibiting the C3 and C5 convertases. The extracellular domain (ECD) of human CD35 contains 30 tandem SCR/SUSHI repeats.

Abbreviation

CD35

UniProt

P17927

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human CD35 fragment

Target

Complement receptor type; CR1; C3BR; CD35; Complement receptor type 1; C3b/C4b receptor; C3b/C4b-R

Clonality

Monoclonal,Recombinant

Clone

A171

Conjugation

Unconjugated

Applications

IHC; IF

Field of Research

Immunology; Stem Cells

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

IHC 1:200-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG, κ

Available Sizes

Curated Selection

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