Recombinant CD35 Monoclonal Antibody
Product Specifications
Background
CD35, also known as complement receptor 1 (CR1), is a 220-300 kDa N-glycosylated member of the RCA (regulators of complement activation) family of proteins. CD35 binds and internalizes particles and immune complexes that are opsonized with MBL or complement components C3b, C3i, C4b, or C1q. CD35 additionally protects the cell from complement-mediated lysis by serving as a cofactor for Factor I and inhibiting the C3 and C5 convertases. The extracellular domain (ECD) of human CD35 contains 30 tandem SCR/SUSHI repeats.
Abbreviation
CD35
UniProt
P17927
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD35 fragment
Target
Complement receptor type; CR1; C3BR; CD35; Complement receptor type 1; C3b/C4b receptor; C3b/C4b-R
Clonality
Monoclonal,Recombinant
Clone
A171
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Immunology; Stem Cells
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:200-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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