Recombinant CD169 Monoclonal Antibody
Product Specifications
Background
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity) . Binds to SPN/CD43 on T-cells (By similarity) . May play a role in hemopoiesis.
Abbreviation
CD169
UniProt
Q9BZZ2
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CD169 fragment
Target
Siglec; SN; SIGLEC1; sialoadhesin; Siglec-1; CD169; Sialic acid-binding Ig-like lectin 1; Siglec-1
Clonality
Monoclonal,Recombinant
Clone
A161
Conjugation
Unconjugated
Applications
IHC; IF; FCM
Field of Research
Immunology; Microbiology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:200-1:1000; IF 1:50; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ
Available Sizes
Curated Selection
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