Recombinant Caspase-7 Monoclonal Antibody
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Abbreviation
Caspase-7
UniProt
P55210
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human Caspase-7 fragment
Target
MCH; LICE; Caspase-7 subunit p; ICE-like apoptotic protease; ICE-LAP; ICE LAP; CMH; CASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; caspase-7; Apoptotic protease MCH3; Apoptotic protease Mch-3; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase7; Caspase-7 subunit p11; CMH 1; CMH1; ICE LAP3; ICE-like apoptotic protease 3
Clonality
Monoclonal,Recombinant
Clone
A151
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
18, 32, 35 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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