Recombinant Complement C4-B Monoclonal Antibody
Product Specifications
Background
Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.
Abbreviation
Complement C4-B
UniProt
P0C0L5
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human Complement C4-B fragment
Target
CPAMD; Basic C; Basic C4; C4 (Chido Blood Group) ; C4-B; C4B; C4B_2; CO4; CPAMD3
Clonality
Monoclonal,Recombinant
Clone
A146
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
193 kDa
Observed Molecular Weight
193, 85 kDa
Isotype
IgG, κ
Available Sizes
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