Recombinant BOB-1 Monoclonal Antibody
Product Specifications
Background
Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator.
Abbreviation
BOB-1
UniProt
Q16633
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human BOB-1 fragment
Target
BOB; POU2AF; OBF; POU2AF1; BOB1; OBF-1; OBF1; OCAB; POU2AF1; BOB1; OBF-1; OBF1; OCAB
Clonality
Monoclonal,Recombinant
Clone
A144
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27 kDa
Observed Molecular Weight
35 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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