Recombinant ASGR1 Monoclonal Antibody
Product Specifications
Background
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.Calcium is required for ligand binding.
Abbreviation
ASGR1
UniProt
P07306
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human ASGR1 fragment
Target
ASGR; C type lectin domain family 4 member H; CLEC4H; ASGP-R; ASGR1; ASGPR; ASGPR1; CLEC4H1; HL-1; ASGPR 1; ASGP-R 1; Asialoglycoprotein receptor 1; C type lectin domain family 4 member H1; C-type lectin domain family 4 member H1; Hepatic lectin H1
Clonality
Monoclonal,Recombinant
Clone
A134
Conjugation
Unconjugated
Applications
FCM; IP; WB; IHC; IF
Field of Research
Signal Transduction; Tags & Cell Markers
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50; FCM 1:50-1:100; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
40-50 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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