Recombinant ASGR1 Monoclonal Antibody

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.Calcium is required for ligand binding.

ASGR; C type lectin domain family 4 member H; CLEC4H; ASGP-R; ASGR1; ASGPR; ASGPR1; CLEC4H1; HL-1; ASGPR 1; ASGP-R 1; Asialoglycoprotein receptor 1; C type lectin domain family 4 member H1; C-type lectin domain family 4 member H1; Hepatic lectin H1