Recombinant alpha smooth muscle Actin Monoclonal Antibody
Product Specifications
Background
Alpha smooth muscle actin encoded by the ACTA2 gene is a key protein in the highly conserved actin family, which plays a crucial role in cell motility, structure and integrity. This isoform is predominantly expressed in vascular smooth muscle cells, where it is essential for maintaining the structure and function of blood vessels and other smooth muscle tissues. Mutations in ACTA2 are linked to various vascular disorders, including familial thoracic aortic aneurysms and dissections (TAAD) and multisystemic smooth muscle dysfunction syndrome.
Abbreviation
Alpha smooth muscle Actin
UniProt
P62736
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human alpha smooth muscle Actin fragment
Target
AAT; GIG; MYMY; Growth inhibiting gene; AAT6; ACTSA; MYMY5; ACTA2; actin; a actin; Actin aortic smooth muscle; Growth inhibiting gene 46; ACTVS; GIG46; Actin alpha 2 smooth muscle aorta; Alpha 2 actin; Alpha actin 2; Alpha cardiac actin; alpha sma; Alpha-actin-2; aortic smooth muscle; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; α-SMA; a actin; AAT6; ACTA; ACTA2; Actin aortic smooth muscle; Actin; ACTSA; ACTVS; GIG46; Growth inhibiting gene 46; MYMY5
Clonality
Monoclonal,Recombinant
Clone
A130
Conjugation
Unconjugated
Applications
WB; IHC; IF; FCM; IP
Field of Research
Signal Transduction; Stem Cells; Cardiovascular; Developmental Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:1000-1:5000; IF 1:50; FCM 1:50-1:100; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/KFRjKFm8
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
42 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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