Recombinant Alpha B Crystallin Monoclonal Antibody

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture.

MFM; CRYA; CTPP; HSPB; Heat Shock Protein Beta; Renal Carcinoma Antigen NY-REN; CTRCT; HEL-S; CRYAB; CMD1II; CRYA2; CTPP2; CTRCT16; HEL-S-101; HSPB5; MFM2; Alpha (B) -Crystallin; Alpha-Crystallin B Chain; Heat Shock Protein Beta-5; Renal Carcinoma Antigen NY-REN-27; Rosenthal Fiber Component; AACRYA; Alpha B crystallin; Alpha crystallin B chain; Crystallin alpha B; Crystallin alpha polypeptide 2; Heat shock 20 kD like protein; Heat shock protein beta 5; Renal carcinoma antigen NY REN 27