Recombinant Muscarinic Acetylcholine Receptor 2/CM2 Monoclonal Antibody
Selected Variant
AN301426L-01
Size: 50 µL
Product Specifications
Background
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3) ; this then triggers calcium ion release into the cytosol.
Abbreviation
Muscarinic Acetylcholine Receptor 2/CM2
UniProt
P08172
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human Muscarinic Acetylcholine Receptor 2/CM2 fragment
Target
Chrm; CHRM2; cholinergic receptor muscarinic 2; HM2
Clonality
Monoclonal, Recombinant
Clone
A121
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
52 kDa
Isotype
IgG, κ
Available Sizes
Price
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