Recombinant Muscarinic Acetylcholine Receptor 2/CM2 Monoclonal Antibody
Product Specifications
Background
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3) ; this then triggers calcium ion release into the cytosol.
Abbreviation
Muscarinic Acetylcholine Receptor 2/CM2
UniProt
P08172
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human Muscarinic Acetylcholine Receptor 2/CM2 fragment
Target
Chrm; CHRM2; cholinergic receptor muscarinic 2; HM2
Clonality
Monoclonal,Recombinant
Clone
A121
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
52 kDa
Isotype
IgG, κ
Available Sizes
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