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Recombinant AATF Monoclonal Antibody

Product Specifications

Background

AATF is an RNA polymerase II binding protein that participates in the transcriptional regulation of E2F target genes and cell proliferation, and protects cells from a variety of stress stimuli by inducing cell cycle arrest, autophagy or apoptosis inhibition. AATF can also be used as a general inhibitor of histone deacetylase HDAC1.

Abbreviation

AATF

UniProt

Q9NY61

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human AATF fragment

Target

BFR; Rb binding protein Che; Rb-binding protein Che; HSPC; CHE; AATF; BFR2; CHE-1; CHE1; DED; Apoptosis antagonizing transcription factor; Apoptosis-antagonizing transcription factor; CHE 1; Protein AATF; Rb binding protein Che 1; Rb-binding protein Che-1; HSPC277; Apoptosis antagonizing transcription factor

Clonality

Monoclonal,Recombinant

Clone

A118

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IF 1:200-1:500

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

63 kDa

Observed Molecular Weight

80 kDa

Isotype

IgG, κ

Available Sizes

Curated Selection

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