Recombinant Osteocalcin Monoclonal Antibody
Product Specifications
Background
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Abbreviation
Osteocalcin
UniProt
P02818
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Osteocalcin protein
Target
PMF; BGLAP; BGP; OC; OCN; osteocalcin; PMF1; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gamma-carboxyglutamate Protein; Gamma carboxyglutamic acid containing protein; OSTCN; OT; Bone Gla protein; Gamma-carboxyglutamic acid-containing protein; Bone gamma carboxyglutamate (gla) protein; OTTHUMP00000016586; ucOC
Clonality
Monoclonal,Recombinant
Clone
10A7
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Stem Cells
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:100-1:500
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11 kDa
Observed Molecular Weight
22 kDa
Isotype
IgG, κ
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