Recombinant Phospho-IRF3 (Ser386) Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Abbreviation
IRF3
UniProt
Q14653
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues around (Ser386) of Human Phospho-IRF3
Target
IRF; IRF3; entrez:3661; IIAE7; IRF-3; IRF-3
Clonality
Monoclonal,Recombinant
Clone
10A6
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:15000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47 kDa
Observed Molecular Weight
60 kDa
Isotype
IgG, κ
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