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Recombinant NF-κB p65 Monoclonal Antibody

Product Specifications

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Abbreviation

NF-κB p65

UniProt

Q04206

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human NF-κB p65 protein

Target

NFKB; Transcription factor p; Nuclear factor of kappa light polypeptide gene enhancer in B-cells; NF-kB p; NFKB3; p65; NF-kB p65; RELA; CMCU; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; NFKB3; p65; transcription factor p65; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NF kappa B p65delta3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; OTTHUMP00000233473; OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; p65 NF kappaB; p65 NFkB; TF65; V rel avian reticuloendotheliosis viral oncogene homolog A; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65) ) ; V rel reticuloendotheliosis viral oncogene homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian) ; NFkB p65

Clonality

Monoclonal,Recombinant

Clone

6F4

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Neuroscience; Microbiology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

65 kDa

Observed Molecular Weight

70 kDa

Isotype

IgG, κ

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