Recombinant NF-κB p65 Monoclonal Antibody
Product Specifications
Background
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Abbreviation
NF-κB p65
UniProt
Q04206
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human NF-κB p65 protein
Target
NFKB; Transcription factor p; Nuclear factor of kappa light polypeptide gene enhancer in B-cells; NF-kB p; NFKB3; p65; NF-kB p65; RELA; CMCU; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; NFKB3; p65; transcription factor p65; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NF kappa B p65delta3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; OTTHUMP00000233473; OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; p65 NF kappaB; p65 NFkB; TF65; V rel avian reticuloendotheliosis viral oncogene homolog A; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65) ) ; V rel reticuloendotheliosis viral oncogene homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian) ; NFkB p65
Clonality
Monoclonal,Recombinant
Clone
6F4
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Neuroscience; Microbiology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/jAyQ8VsV
Calculated Molecular Weight
65 kDa
Observed Molecular Weight
70 kDa
Isotype
IgG, κ
Curated Selection
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