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Recombinant S100B Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.

Abbreviation

S100B

UniProt

P04271

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human S100B protein

Target

NEF; S100; S100-B; S100beta; S100B; S100 beta; S100 calcium-binding protein B; S-100 protein beta chain; S-100 protein subunit beta; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S100 calcium binding protein B; S100 calcium binding protein beta (neural) ; S100 protein beta chain

Clonality

Monoclonal,Recombinant

Clone

4F6

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

11 kDa

Observed Molecular Weight

11 kDa

Isotype

IgG, κ

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