Recombinant FAP Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
FAP
UniProt
Q12884
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human FAP protein
Target
170 kDa melanoma membrane bound gelatinase;170 kDa melanoma membrane-bound gelatinase; DPPIV; DPPIVA; FAPA; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR; Seprase; SIMP; FAP; FAPalpha; FAP-1
Clonality
Monoclonal,Recombinant
Clone
7A8
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Signal Transduction; Cancer
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
87 kDa
Observed Molecular Weight
87 kDa
Isotype
IgG, κ
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