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Recombinant FAP Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

FAP

UniProt

Q12884

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human FAP protein

Target

170 kDa melanoma membrane bound gelatinase;170 kDa melanoma membrane-bound gelatinase; DPPIV; DPPIVA; FAPA; Fibroblast activation protein alpha; Integral membrane serine protease; SEPR; Seprase; SIMP; FAP; FAPalpha; FAP-1

Clonality

Monoclonal,Recombinant

Clone

7A8

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Signal Transduction; Cancer

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

87 kDa

Observed Molecular Weight

87 kDa

Isotype

IgG, κ

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