Recombinant Collagen II Monoclonal Antibody

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

STL; collagen type; CO2A; COL2A; COL11A; Collagen; COL2A1; ANFH; AOM; COL11A3; SEDC; STL1; Alpha 1 type II collagen; Cartilage collagen; Chondrocalcin; CO2A1; Collagen II alpha 1 polypeptide; PIICP; PIINP; Collagen II; Collagen 2; collagen type 2; Alpha-1 type II collagen; CTX2