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Recombinant Collagen II Monoclonal Antibody

Product Specifications

Background

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Abbreviation

Collagen II

UniProt

P02458

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Collagen II protein

Target

STL; collagen type; CO2A; COL2A; COL11A; Collagen; COL2A1; ANFH; AOM; COL11A3; SEDC; STL1; Alpha 1 type II collagen; Cartilage collagen; Chondrocalcin; CO2A1; Collagen II alpha 1 polypeptide; PIICP; PIINP; Collagen II; Collagen 2; collagen type 2; Alpha-1 type II collagen; CTX2

Clonality

Monoclonal,Recombinant

Clone

9A8

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Stem Cells

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product MSDS

https://789.bio/eb/Qce9Vlnn

Calculated Molecular Weight

142 kDa

Observed Molecular Weight

200 kDa

Isotype

IgG, κ

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