Recombinant HDAC6 Monoclonal Antibody
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Abbreviation
HDAC6
UniProt
Q9UBN7
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human HDAC6 protein
Target
KIAA; Histone deacetylase; Protein phosphatase 1 regulatory subunit; PPP1R; HDAC6; CPBHM; HD6; JM21; PPP1R90; FLJ16239; HD 6; HDAC 6; Histone deacetylase 6; Histone deacetylase 6 (HD6) ; JM 21; OTTHUMP00000032398; OTTHUMP00000197663; Protein phosphatase 1 regulatory subunit 90; KIAA0901
Clonality
Monoclonal,Recombinant
Clone
8C2
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling; Stem Cells
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
131 kDa
Observed Molecular Weight
160 kDa
Isotype
IgG, κ
Curated Selection
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