Recombinant GSK3β Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
GSK3β
UniProt
P49841
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human GSK3β protein
Target
GSK3B; gsk-3β; Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3B; glycogen synthase kinase-3 beta
Clonality
Monoclonal,Recombinant
Clone
7C10
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Cardiovascular; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
47 kDa
Observed Molecular Weight
47 kDa
Isotype
IgG, κ
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