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Recombinant GSK3β Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

GSK3β

UniProt

P49841

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human GSK3β protein

Target

GSK3B; gsk-3β; Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3B; glycogen synthase kinase-3 beta

Clonality

Monoclonal,Recombinant

Clone

7C10

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Cardiovascular; Cancer; Metabolism

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:2000-1:10000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

47 kDa

Observed Molecular Weight

47 kDa

Isotype

IgG, κ

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