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Recombinant IRF-1 Monoclonal Antibody

Product Specifications

Background

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Abbreviation

IRF-1

UniProt

P10914

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human IRF-1 protein

Target

Interferon regulatory factor; Interferon regulatory factor 1 isoform d; Interferon regulatory factor 1 isoform +I; IRF; IRF1; IRF-1; MAR; MAR1; Interferon regulatory factor 1; Interferon regulatory factor 1 isoform +I9; Interferon regulatory factor 1 isoform d78; Interferon regulatory factor 1 isoform delta4; Interferon regulatory factor 1 isoform delta7; IRF 1; IRF 1

Clonality

Monoclonal,Recombinant

Clone

7C5

Conjugation

Unconjugated

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling; Cardiovascular

Purification

Protein A

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

37 kDa

Observed Molecular Weight

48 kDa

Isotype

IgG, κ

Frequently Asked Questions

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