Recombinant Cleaved Caspase-7 (Asp198) Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Abbreviation
Cleaved Caspase-7
UniProt
P55210
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Cleaved Caspase-7 (Asp198) protein
Target
MCH; LICE; Caspase-7 subunit p; ICE-like apoptotic protease; ICE-LAP; ICE LAP; CMH; CASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; caspase-7; Apoptotic protease MCH3; Apoptotic protease Mch-3; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase7; Caspase-7 subunit p11; CMH 1; CMH1; ICE LAP3; ICE-like apoptotic protease 3; Caspase 7
Clonality
Monoclonal,Recombinant
Clone
5C3
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
WB 1:2000-1:10000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
18 kDa
Isotype
IgG, κ
Curated Selection
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